As the year progressed, 2025 reassured investors that the sector clouds gathering into the New Year were out of touch with fundamental realities. Historically attractive valuations also compelled acquirers to act in force, lending additional assurances and ultimately leading to a banner year for M&A. While the healthcare sector ends the year on a firmer footing, we would argue that until more recently the market’s attention has been elsewhere. As funding and the returns on technology-related capital investments are increasingly being called into question, healthcare would seem a natural home for growth investors looking to diversify.

Looking ahead, we see the healthcare sector as a prime beneficiary of artificial intelligence-enabled technologies when it comes to furthering innovation, but also improving access and affordability.

Although sentiment may have improved, exchange-traded fund flows attest that mainstream investors are not exposed to the healthcare area in any significant way. Meanwhile, the sector continues to innovate, as evidenced by stunning clinical data, regulatory approvals and commercial launches exceeding expectations. Though equity investors may have missed the related memo, large biopharmaceutical companies seeking to replenish the tens of billions of dollars of revenues that will likely fall to generic competition over the next few years have clearly wasted little time putting cash to work.

Looking ahead, we see the healthcare sector as a prime beneficiary of artificial intelligence-enabled technologies when it comes to furthering innovation, but also improving access and affordability, as waste and inefficiencies are reduced allowing for more intelligent and prospective healthcare investment around the globe.  As the US looks to level the investment playing field, there will be opportunity for others to step up to the plate. Irrespective of geography, our investments will naturally follow wherever innovation abounds and the best and brightest companies are enabled to lead.

Related Funds

All opinions and estimates in this document constitute the best judgement of Polar Capital as of the date hereof, but are subject to change without notice, and do not necessarily represent the views of Polar Capital.  Polar Capital is not rendering legal or accounting advice through this material; viewers should contact their legal and accounting professionals for such information. This document does not constitute a prospectus, offer, invitation or solicitation to buy or sell securities and is not intended to provide the sole basis for any evaluation of the securities or any other instruments, which may be discussed in it. This is not a financial promotion.  Past performance is not indicative of future results.  A list of all recommendations made within the immediately preceding 12 months is available upon request.  This document is not a personal recommendation and you should consider whether you can rely upon any opinion or statement contained in this document without seeking further advice tailored for your own circumstances. This document is only made available to professional clients and eligible counterparties.  Shares in the fund should only be purchased by professional investors.  The law restricts distribution of this presentation in certain jurisdictions; therefore, persons into whose possession this presentation comes should inform themselves about and to observe, all applicable laws and regulations of any relevant jurisdiction. Issued by Polar Capital LLP and Polar Capital (Europe) SAS. Polar Capital LLP is authorised and regulated by the United Kingdom’s Financial Conduct Authority (“FCA”) and the United States’ Securities and Exchange Commission (“SEC”). Registered address: 16 Palace Street, London SW1E 5JD. Polar Capital (Europe) SAS is authorised and regulated by France’s Autorité des marchés financiers (AMF). Registered address: 18 Rue de Londres, Paris 75009, France.

None

As the year progressed, 2025 reassured investors that the sector clouds gathering into the New Year were out of touch with fundamental realities. Historically attractive valuations also compelled acquirers to act in force, lending additional assurances and ultimately leading to a banner year for M&A. While the healthcare sector ends the year on a firmer footing, we would argue that until more recently the market’s attention has been elsewhere. As funding and the returns on technology-related capital investments are increasingly being called into question, healthcare would seem a natural home for growth investors looking to diversify.

Looking ahead, we see the healthcare sector as a prime beneficiary of artificial intelligence-enabled technologies when it comes to furthering innovation, but also improving access and affordability.

Although sentiment may have improved, exchange-traded fund flows attest that mainstream investors are not exposed to the healthcare area in any significant way. Meanwhile, the sector continues to innovate, as evidenced by stunning clinical data, regulatory approvals and commercial launches exceeding expectations. Though equity investors may have missed the related memo, large biopharmaceutical companies seeking to replenish the tens of billions of dollars of revenues that will likely fall to generic competition over the next few years have clearly wasted little time putting cash to work.

Looking ahead, we see the healthcare sector as a prime beneficiary of artificial intelligence-enabled technologies when it comes to furthering innovation, but also improving access and affordability, as waste and inefficiencies are reduced allowing for more intelligent and prospective healthcare investment around the globe.  As the US looks to level the investment playing field, there will be opportunity for others to step up to the plate. Irrespective of geography, our investments will naturally follow wherever innovation abounds and the best and brightest companies are enabled to lead.

All opinions and estimates in this document constitute the best judgement of Polar Capital as of the date hereof, but are subject to change without notice, and do not necessarily represent the views of Polar Capital.  Polar Capital is not rendering legal or accounting advice through this material; viewers should contact their legal and accounting professionals for such information. This document does not constitute a prospectus, offer, invitation or solicitation to buy or sell securities and is not intended to provide the sole basis for any evaluation of the securities or any other instruments, which may be discussed in it. This is not a financial promotion.  Past performance is not indicative of future results.  A list of all recommendations made within the immediately preceding 12 months is available upon request.  This document is not a personal recommendation and you should consider whether you can rely upon any opinion or statement contained in this document without seeking further advice tailored for your own circumstances. This document is only made available to professional clients and eligible counterparties.  Shares in the fund should only be purchased by professional investors.  The law restricts distribution of this presentation in certain jurisdictions; therefore, persons into whose possession this presentation comes should inform themselves about and to observe, all applicable laws and regulations of any relevant jurisdiction. Issued by Polar Capital LLP and Polar Capital (Europe) SAS. Polar Capital LLP is authorised and regulated by the United Kingdom’s Financial Conduct Authority (“FCA”) and the United States’ Securities and Exchange Commission (“SEC”). Registered address: 16 Palace Street, London SW1E 5JD. Polar Capital (Europe) SAS is authorised and regulated by France’s Autorité des marchés financiers (AMF). Registered address: 18 Rue de Londres, Paris 75009, France.

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